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Product Details
ABS 015-22-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Published species
Dog
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
22
Immunogen
Purified human D-dimer.
Conjugate
Form
Liquid
Concentration
1.10 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_962061
Product Specific Information
ABS 015-22-02 detects D-dimer from human and dog samples.
ABS 015-22-02 has been successfully used in ELISA procedures.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
Fibrinogen is the main protein of blood coagulation system. It consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. The process of blood coagulation results in the activation of fibrinogen into fibrin by thrombin and fibrin polymerization. Fibrin clot is then digested by plasmin, and fibrin degradation products of different molecular weights are released into the bloodstream.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: carboxy-terminal region; fibrinogen A-alpha-chain; Fibrinogen alpha chain; fibrinogen, A alpha polypeptide; MGC119422; MGC119423; MGC119425
Gene Aliases: FGA; Fib2
UniProt ID: (Human) P02671
Entrez Gene ID: (Human) 2243, (Dog) 475473
adaptive immune response
platelet degranulation
protein complex assembly
acute-phase response
cell-matrix adhesion
signal transduction
blood coagulation
extracellular matrix organization
plasminogen activation
response to estradiol
response to genistein
positive regulation of heterotypic cell-cell adhesion
fibrinolysis
induction of bacterial agglutination
response to morphine
cellular protein complex assembly
cellular protein metabolic process
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
response to cycloheximide
positive regulation of protein secretion
protein polymerization
response to calcium ion
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to interleukin-6
cellular response to organic cyclic compound
blood coagulation, common pathway
blood coagulation, fibrin clot formation
positive regulation of peptide hormone secretion
liver regeneration
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cellular response to granulocyte colony-stimulating factor
negative regulation of endothelial cell apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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